Abstract:
In this article, there are given results of comparative studying of efficiency of surgical and conservative
treatment of 277 patients with multidrug resistant tuberculosis. The effectiveness of the
surgical treatment of the main group of patients against the background of chemotherapy with anti-TB
chemotherapy with the drugs of the reserve line has been compared with two control groups:
Group I—Surgical intervention was implemented with drugs of the first line, Group II—Chemotherapy
was conducted with anti-TB drugs of the second line without surgical intervention.
Treatment outcomes in three groups were stated after cohort investigation, and following results
were obtained: Effectiveness of surgical treatment of patients of the main group with MDR TB
treated with anti-TB drugs of the second line constituted 98.0% versus 53.7% in the Group II. Effectiveness
of conservative treatment of patients in III (control) Group constituted 74.4%. Analysis
of results obtained showed that the outcomes in the main group after regimen completed were
higher by 1.8 times than in patients operated against the background of treatment with the drugs
of the first line and by 1.3 times higher than effectiveness in patients in the Group III (P < 0.01).
Effectiveness of the treatment in the Group II was obtained through implementation of collapsesurgical
interventions. In this article, the statistical program STAT 10 was applied.
