Open Access Journals: Recent submissions
Now showing items 701-720 of 831
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Modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin: Role of cNOS-dependent IKK-β S-nitrosylation in the regulation of COX-2 activation
(Scientific Research Publishing, 2012-04)Disturbances in nitric oxide synthase (NOS) and cyclooxygenase (COX) isozyme systems, manifested by the excessive NO and prostaglandin (PGE2) generation, are well-recognized features of gastric mucosal inflammatory responses ... -
The ATPase activity of molecular chaperone HSP60 is inhibited by immunosuppressant mizoribine
(Scientific Research Publishing, 2012-04)The molecular chaperone HSP60 is a chaperonin homolog of GroEL. We had previously shown that the immunosuppressant mizoribine is bound directly to HSP60 and inhibited its chaperone activity. However, the inhibitory mechanisms ... -
Oxidized phospholipids modify plasminogen and apolipoprotein(a): Implications for vascular disease
(Scientific Research Publishing, 2012-04)Whereas the close structural homology between human plasminogen and apolipoprotein(a) has been known for a number of years only recent studies have revealed that both proteins carry linked oxidized phospholipids that may ... -
The effects of astragalus polysaccharide on zebrafish cell apoptosis and senescence
(Scientific Research Publishing, 2012-04)Astragalus polysaccharide (AP) is the extraction of astragalus, which is a plant used in traditional Chinese herb medicine and may increase an orgainism’s resistance to stress. Several earlier studies in vitro have indicated ... -
Somaclonal variations of Soybeans (Glycine Max. L. Merr) stimulated by drought stress based on random amplified polymorphic DNAs (RAPDs)
(Scientific Research Publishing, 2012-01)In soybeans, drought stress causes 50% yield losses. Breeding for drought tolerance in soybeans has been widely developed using various methods, among which is polyethylene glycol (PEG-6000) induction to simulate drought ... -
DOF transcription factors in developing peanut (Arachis hypogaea) seeds
(Scientific Research Publishing, 2012-01)DNA binding with one finger (DOF) transcription factors play important roles in storage material accumulation and morphogenesis of developing seeds. Oil and protein contents varied in different cultivars in important oil ... -
Intergenic subset organization within a set of geographically-defined viral sequences from the 2009 H1N1 influenza A pandemic
(Scientific Research Publishing, 2012-01)We report a bioinformatic analysis of the datasets of sequences of all ten genes from the 2009 H1N1 influenza A pandemic in the state of Wisconsin. The gene with the greatest summed information entropy was found to be the ... -
Comparative gene expression analysis in stems of Dolichos purpureus and Arabidopsis thaliana
(Scientific Research Publishing, 2012-01)The outermost layer epidermis of a plant stem plays an important role in protection and environment-sensing. The mechanisms of sensing and response to the environment through the stem epidermis remain unclear. Here we ... -
SPT5 affects the rate of mRNA degradation and physically interacts with CCR4 but does not control mRNA deadenylation
(Scientific Research Publishing, 2012-01)The CCR4-NOT complex has been shown to have multiple roles in mRNA metabolism, including that of transcriptional elongation, mRNA transport, and nuclear exosome function, but the primary function of CCR4 and CAF1 is in the ... -
Molecular docking investigation for Indonesian H274Y mutant neuraminidase type 1 with neuraminidase inhibitors
(Scientific Research Publishing, 2012-01)The aim of this study is to get insight the interaction between Indonesian H274Y mutant neuraminidase with four inhibitors. Not only to seek preferable inhibitor to be used, but also to investigate the interaction occurred, ... -
Molecular surveillance of dengue virus in Bahia State, Brazil
(Scientific Research Publishing, 2012-01)Dengue is an important emerging viruses, posing a threat to one-third of the global human population. In 2002, the introduction of DENV-3 in the state of Bahia produced massive epidemic (about 35,000 cases detected) and ... -
Effect of hypoxia and glutamine or glucose deprivation on the expression of retinoblastoma and retinoblastoma-related genes in ERN1 knockdown glioma U87 cell line
(Scientific Research Publishing, 2012-01)The expression of retinoblastoma and several retinoblastoma-related genes was studied in glioma cell line U87 and its subline with knockdown of ERN1 (endoplasmic reticulum—nuclei-1), the main endoplasmic reticulum stress ... -
Interaction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys
(Scientific Research Publishing, 2012-01)Octameric hemoglobins have been developed by the introduction of surface cysteines in either the alpha or beta chain. Originally designed as a blood substitute, we report here the structure and ligand binding function; in ... -
HPV positivity varies with technique and primer set, in formalin-fixed paraffin-embedded benign and malignant breast tissue from Malta
(Scientific Research Publishing, 2011-10)The role of human papillomavirus in breast cancer pathogenesis is an area of considerable debate following differing results from all over the world. This study analyzed paraffin embedded tissue from 19 patients with benign ... -
Codon bias of influenza a viruses and their hosts
(Scientific Research Publishing, 2011-10)The Influenza A virus remains an annual and worldwide health concern due to its fast evolutionary rate. There are two major forms of Influenza evolution: drift, caused by mutations, and shift, which results from the exchange ... -
An investigation of 10 Y-STR loci and the detection of specific haplotype frequencies in Turkish population
(Scientific Research Publishing, 2011-07)This study is to survey 10 Y-STR loci in 241 males from Turkey. In this study, the 241 healthy and unrelated males living in different parts of Turkey for at least three generations were included. Genomic DNAs were isolated ... -
Effects of genetic and environmental factors and gene-environment interaction on expression variations of genes related to stroke in rat brain
(Scientific Research Publishing, 2011-07)To determine if genetic and environmental (dietary) factors and gene-environment interaction impact on the expression variation of genes related to stroke, we conducted microarray experiments using two homozygous rat strains ... -
A reduced computational load protein coding predictor using equivalent amino acid sequence of DNA string with period-3 based time and frequency domain analysis
(Scientific Research Publishing, 2011-07)Development of efficient gene prediction algorithms is one of the fundamental efforts in gene prediction study in the area of genomics. In genomic signal processing the basic step of the identification of protein coding ... -
N–nitrosodiethylamine cytochrome P450 induction and cytotoxicity evaluation in primary cultures of rat hepatocytes
(Scientific Research Publishing, 2011-07)The primary routes of potential human exposure to N-nitrosodiethylamine (NDEA) are ingestion, inhalation, and dermal contact. Air, diet and smoking contribute to potential human exposure at levels of a few µg of NDEA/day. ... -
Influence OF anticancer drugs on DNA methylation in liver of female mice
(Scientific Research Publishing, 2011-06)Epigenetic changes such as DNA methylation regulate gene expression in normal development. Methotrexate and Adriamycine are antineoplastic drugs that target DNA and enzymes acting on DNA. We aimed to evaluate their cytotoxic ...
